Friday, March 16, 2018

Achieving Excellence in Healthcare - Expanding the Role of Biomedical Scientists


 































Hospital care is mainly the domain of physicians who have been trained to assess the signs and symptoms presented by patients and to determine the most likely cause of their ill health. If the doctor is clear enough about what case situation is about based on the guidelines of clinical care, then a remedy is prescribed to the patient. The second option to the physician is to request for a number of physical parameters, laboratory tests and medical images to be taken to strengthen the recommendation for the appropriate remedies. Often these routine laboratory tests, which are designed in a plug-and-play fashion, are not too technically challenging. This way anyone with diploma or bachelor’s level training in laboratory techniques is able to conduct these tests routinely. In many conditions these standard tests are more than enough to obtain effective treatment. However, like many other situations in life, things are not as simple as we wish for and so there exist many diseases with many overlapping signs and symptoms. In the situation where a clear determination is not arrived at in the shortest possible time, the first most obvious options for remedy are provided to the patient. It is really a race against time.

At the level of the population, situations as have been described above begin to accumulate and expand over time. The causes of ill health that are not directly targeted due to technical challenges begin to cause present serious conditions. A clear example is the case of malaria, where most fever cases are treated as malaria although there are more than ten pathogens that can also cause fevers and fever-like symptoms. The same can be said about diarrhea, where the obvious causes are bacteria, but we now know viruses do cause some cases of diarrhea. The incomplete laboratory diagnosis has been allowed to go on for far too long in the public health systems across the world and danger signs are beginning to show. Some advanced countries have started to change the situation by elevating the role of biomedical scientists in the hospitals from one that performs routine tests to a highly trained researcher. In the US, people with PhD are now being employed to work as postdoctoral clinical fellows. These people have the advanced scientific and technical training to operate advanced instruments for clinical sample analysis. The people currently working in clinical laboratories in Ghana cannot perform these types of tests routinely.

It is for this purpose that WACCBIP of University of Ghana took the initiative to organize a two-week workshop to train laboratory personnel of the National Catholic Health Service. This is the first step in changing the culture of healthcare in this country and to move towards the new standards of operating research level analysis in the hospitals. People with PhD are already in stop supply in Ghana to work in the tertiary education sector. So, the strategy is to train those who have already committed their career to clinical laboratory work. In the first of this kind of workshop organized at the University of Ghana from 29th January to 2nd February 2018 with the part 2 in June 4-8, 2018, the biomedical scientists clearly demonstrated the capacity to be trained at the masters and PhD levels. It is therefore not a far-fetched objective to put in place a new policy for a 21st century healthcare system in Ghana.  The advantages are many and are beyond the obvious quick remedy for patients, the overall health care cost will dramatically reduce. The most important outcome is to control disease conditions that becoming more and more threatening. They are inadvertently allowed to fester and grow in the patients while futile efforts are made to treat non-existing disease due to overlapping symptoms. The cadre of biomedical scientist in the hospitals and clinics possess qualities that money cannot buy, which makes their upgrade from Biomedical Scientist to Biomedical Research Scientists a much easy exercise. Qualities such as curiosity, intellectual power and strong interest in patient care.

It is therefore an opportune time to develop a new kind of graduate programme for biomedical who have been on the job for 5-10 years. It will be important to organize a curriculum development summit at the national level to bring together key biomedical researcher and laboratory stuff to undertake this important exercise. The programme to be developed can be offered by multiple institutions drawn into one system, making it possible to unify the standard of training and to equitably share best practices nationwide. The big goal to shot for is the establishment of a national disease surveillance and control systems that is anchored on some hospital laboratories and a number research centers and institutions.


google.com, pub-9398771462498500, DIRECT, f08c47fec0942fa0
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Patrick Kobina Arthur (PhD),
Head of Training and Research,
West Africa Centre for Cell Biology 
of Infectious Pathogens
University of Ghana,
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Thursday, March 15, 2018

All PAKAR Quotes




its one thing being happy or sad and another being truly happy or sad. When your soul tastes true happiness, nothing else matters. The world goes back into its elements and the only thing that remains intact is the happiness you feel inside. And yes, this kind of happiness does not depend on mortals or drugs or things. Its pure, simply pure and simple. Pakar Erst March 11, 2013 

The real engine of progress and prosperity is a strong aversion to poverty, squalor, hopelessness and suffering. To this we should add strong faith, vision, skills, diligence and dedication. The strong aversion must always come first as the primary push factor, after that comes faith as a secondary pull factor. This is the long, narrow, uphill way to transgenerational prosperity. Pakar Erst March 10, 2016 


Pakar Erst April 2, 2013 


I shared with my Cell Biology class today a prediction that: In 50 years or less, Cell based technologies will allow us to make superior tissues and organs for people. That is an exciting future. Pakar Erst April 4, 2017 


Our Talent Constitute What Is Beautiful In Us. There Is No Reason Not To Strive To Shine. Shine In A Way Distinct To You. Beauty By Expression. Humility Is Not By Suppression Of This True Kind Of Beauty.Pakar Erst April 6, 2014

People tend to believe the mystical rather than the TRUTH. Lies that are mystically presented have the power to hypnotize and make-believe. The TRUTH is not mystical and cannot be mystical. The TRUTH is natural and freely set aloft. Without effects or special effects. The TRUTH derives its power from time and space. Time as in eternity and space that stretches to the outer reaches of the cosmos. So this is the problem TRUTH suffers, time and space is too expensive. Time and space consumes too much cognitive power. So many are destroyed daily through their inability to be natural and to avoid mysticism. So the spiritual and the show-people have the upper market in this realm. But then time passes and more space is covered for TRUTH to stand and the mystical lies to lose their power.


Today's take home message at my Cell Biology lecture: A degree course in Biochemistry, Cell and Molecular Biology ought to lead to the development of executive level skills. Executive skills allow you to play a critical and decisive role in the fortune of many people. This means we cannot tolerate rote-learning but big picture thinking and skills for solving complex problems. #themoreyouknow



Pakar Erst May 2, 2015 
The IRONY is indeed too much. I mean: HOW does a DUMMY know what SMART is? Like you entered a showroom full of dummies (also called manikin) and they all point you to where the cashier is and also your way out of the shop!!! Very SHOCKING.


Pakar Erst TRIAGE. TRIAGING. Lets see what we can do with this. I see many people look at intelligence and wisdom as though it is a sheet of paper. Just one leaf is enough. Great things are done with pages and pages of intelligence and wisdom. BUT in this town, the top people only hold less than half a page of this thing called "intelligence and wisdom". TRIAGE is alien in this town. So funerals are festive occasions, we cannot triage at all so burials have got to be big festive events to appear pleasant based on their frequency in this town.



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Monday, March 5, 2018

Creating High Value Biotech Enterprises in Ghana


Biotech industries cut across a wide range of activities that involve the use of living organisms to make products. These range from the traditional fermentation processes used making in pito and dough, to the high tech and high value biologics and drug molecules. Ghana is in the prime location of the world and it’s also at the prime time to launch a major push for the creation of at least ten big biotech companies. These companies in 10-20 years will grow and generate revenue that will exceed that of petroleum, gold and diamond combined. And Biotech industries typically have minimal impact on the environment, a case of low value inputs and extremely high value outputs.

Ghana currently does not have any biotech company worth mentioning, except the beer brewing industries, which deal in medium value bulk products. These types of products are usually meant to serve the local economy since it does not stand to economic reason to export them to distant countries in large volumes. To get biotech business started we can look at products we import most, such as insulin and glucometers and dare to create one company that can produce the same at competitive prices. The patents covering these products have already expired and so Ghana can take advantage of this and cut down imports. This will save on foreign exchange losses for the country and also the technology platform that is created could be leveraged to make other specialist products that are discovered in Ghana for the global market.

The current lack of biotech companies in Ghana is due to lack of leadership from all three players, the government, academia and industry. We have had 60 years of science education in Ghana and it is time for researchers in the institutions of higher learning to realize the power of their ideas and seek to put them to work to benefit the larger society. This time, we should not develop ideas and hope some business person will show interest. We should take the initiative right to the top. It’s time to embrace integrated innovation as the way of creating wealth for our nation. Our talent is useless if we have to compete with the national budget for small scale funding of our research work. And continue to complain about the persistent lack of funding from Government. There is the need to change the mindset from primarily teaching with some research to research, enterprise creation with some teaching. Otherwise, the level of training we provide will continue to be low. And the students will walk away from their fields of study right after training to secure any job they can find, and the vicious cycle will continue to repeat itself.

The other reasons why the biotech sector has not blossomed in Ghana is also due to the lack of critical capacity, as the departments of biochemistry and biotechnology in the country have for a long time been training only small numbers of students many of who do not stay in the field. This situation has changed dramatically; since 2013 my department at the University of Ghana has recruited and is training 50 PhD students, due to the World Bank’s African centers of excellence initiative. This kind of research capacity changes everything that held us back and put us at the cusp of a major launch forward in the Biotech sector. The call for the establishment of about 10 high value biotech companies in Ghana is timely and far-sighted. This will lift up the country in a powerful way, as we already have the prime location for Biotech processing with 30oC in temperature all year around and many of the organisms are well adapted to our region of the world.

A high value biotech company will take about 4-5 years to transition from the laboratory scale to industrial scale and so it may not directly fit into the one-district-one factory initiative, due to the political nature of the programme, which seeks quicker turnaround times in industrial developments. However, the creation of the high value biotech enterprises should be launched as a follow up to the one-district-one-factory for the medium to the long term. We need to have the strategic patience needed to develop a really authentic and competent enterprises that are built to last. My recommendation to the implementers of the one-district-one-factory initiative is that they should endeavor to create or support the creation of one high value biotech enterprise for every ten district factories that are established. Many of these factories will need these biotech companies for their long-term sustainability.


A high value Biotech company is more profitable than gold and petroleum producing companies on the basis return on investment and the size of their operations. The products they make are typically low volume and high value and can easily go global. This will serve the nation well by harnessing the strengths of many local district factories to create globally competitive products. A case in point is the Ayensu starch whereby a high value biotech could procure all of its outputs to manufacture medicinal products such as biologics for the global market. That guaranteed market will ensure Ayensu Starch grows more cassava through its out-grower schemes creating more linkages for the economy to expand. A biotech company established by Prof. Leroy Hood in 1980 in USA has grown to achieve a market value of 129 billion USD and 29 Billion USD net worth. These enterprises can change the fortunes of this country something the mining and extractive industries have failed to do.

We need to be strategically deliberate with the model of the biotech industry we develop in Ghana and make sure the technical construction is 70-80% locally done. There is no need to rush and spend huge amounts of money to acquire expensive industrial tools from abroad only for it to breakdown and derail the creation of industries. We need to establish other allied industries such as tool making companies right from the planning stage to ensure that a local, sustainable and vertically integrated Biotech sector is achieved. We need to also prioritize these high value biotech enterprises to support the creation of other vertically integrated manufacturing systems in Ghana for the long-term. These strategic approaches would generate numerous jobs for the Ghanaian economy.  The policy of the establishment of technology parks across the country can also come in handy. It can provide entrepreneurs with places to assemble their teams for training and piloting their technology in the development phase while their industrial estates are built. Let’s commit to this venture and the nation’s future will be great.


google.com, pub-9398771462498500, DIRECT, f08c47fec0942fa0


Patrick Kobina Arthur (PhD),
---------------------------------------
Head of Training and Research,
West Africa Centre for Cell Biology 
of Infectious Pathogens (WACCBIP)