The two groundbreaking discoveries demonstrates clearly that high fat diet has a negative feedback on processes the is required for the regulation of blood glucose level. The persistent elevated fat level in the blood disrupts the process by which the insulin-producing beta cells in the pancreas sense blood level glucose. This sensing process is vital to the control of the released of the correct amounts of insulin timely to regulate blood glucose levels. It appears high fat diet is a two-edged sword that blocks breakdown of fat and also leads to elevated fat levels in the blood which disrupts the glucose sensing function of beta cells of the pancreas. The take home message is the high fat diet is not good especially for people above 30 years, since it is strongly linked to diabetes and coronary diseases.
Patrick Kobina Arthur (PhD),